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Reducing pain in patients with osteoarthritis of the big toe
Prefabricated foot orthoses and rocker-sole footwear in which the sole of the shoe is curved are effective at reducing peak pressure under the big toe in people with a condition called first metatarsophalangeal joint osteoarthritis, but new research shows that they achieve this through different mechanisms. Also, rocker-sole shoes exhibited lower peak pressure under the lesser toes and midfoot, while orthoses increased peak pressure in these areas. Investi ...
EurekAlert - Tue. Dec 8
Hip osteoarthritis may not appear on x-ray
Boston -- In the majority of cases, hip x-rays are not reliable for diagnosing hip osteoarthritis OA , and can delay the treatment of this debilitating disease. These findings are the first to evaluate the diagnostic performance of an x-ray in patients with clinical signs and symptoms of classic OA. The study appears in the British Medical Journal . Hip osteoarthritis OA is a significant source of morbidity causing pain, difficulty walking, and disability. ...
EurekAlert - Tue. Dec 8
Genetic variants tied to increased risk of bone complications in young leukemi...
Variations in genes involved in normal bone development are associated with an 8-to 15-fold increased risk for osteonecrosis in young patients with acute lymphoblastic leukemia ALL , according to research led by St. Jude Children s Research Hospital and Children s Oncology Group investigators. The results were discussed today at the 57th Annual Meeting of the American Society of Hematology. Osteonecrosis is a major side effect of ALL treatment with chemoth ...
EurekAlert - Mon. Dec 7
Diabetes and its effect on bone is key topic at Abu Dhabi meeting
Nyon, Switzerland - December 7, 2015 Diabetes is a widespread chronic disease which is a public health issue of increasing importance in the Middle East. Health professionals who treat diabetic patients often do not recognize that fragility fractures are a major complication of the disease. In response to the dramatic increase in both fragility fractures and type 2 diabetes mellitus T2DM within the region, the IOF Regionals 3rd Middle East Africa Osteoporo ...
EurekAlert - Mon. Dec 7
After hip-replacement surgery, medication use decreases
December 1, 2015 - A new study, published November 15, in the journal PAIN reg provides information on the trajectories of prescription drug use before and after hip-replacement surgery--total hip arthroplasty THA , one of the most common types of joint replacement surgery. Hip-replacement surgery is commonly followed by long-term reductions in the use of prescription drugs for pain and insomnia. But use of these medications increases during the year befor ...
EurekAlert - Sun. Dec 6
Herniated disks in children and teens linked to lower spine malformations
December 1, 2015 - Most children and adolescents with herniated disks in the lower lumbar spine have some sort of malformation of the spinal vertebrae, reports a study in the December issue of Neurosurgery , official journal of the Congress of Neurological Surgeons , published by Wolters Kluwer . The study by Dr. Zhongjun Liu and colleagues of Peking University Third Hospital, Beijing, China, helps in understanding how children and teens develop lumbar dis ...
EurekAlert - Sun. Dec 6
IOF urges early evaluation of fracture risk in diabetics
This news release is available in Spanish . Nyon, Switzerland - December 2, 2015 Despite an up to six-fold increased risk of broken bones in patients with type 1 diabetes mellitus T1DM , the relationship between diabetes and osteoporosis has, until recently, suffered from a general lack of attention and research. As a result, health professionals who treat diabetic patients often do not recognize that fragility fractures are a major complication of the dis ...
EurekAlert - Sun. Dec 6
Method of postoperative pain relief may influence recovery from total knee rep...
A new study published today in The Journal of the American Osteopathic Association compared outcomes from two types of postoperative pain control methods in a group of patients who had both of their knees replaced. The retrospective study reviewed records of 16 patients who underwent bilateral total knee arthroplasty TKA in which a femoral nerve block was administered at the first operation and a periarticular injection of extended-release bupivacaine lipo ...
EurekAlert - Tue. Dec 1
Ultrasound reveals knuckle-cracking fireworks
CHICAGO - Research presented today at the annual meeting of the Radiological Society of North America RSNA tackles one of life s great mysteries what causes a knuckle to crack out loud It s extremely common for joints to crack, pop and snap, said Robert D. Boutin, M.D., professor of radiology at University of California, Davis UC Davis Health System. We were interested in pursuing this study because there s a raging debate about whether the knuckle-crackin ...
EurekAlert - Tue. Dec 1
Adults with cerebral palsy more likely to have chronic health conditions
Adults with cerebral palsy CP have higher odds for chronic health conditions such as asthma, hypertension and arthritis compared with adults without CP, according to a study in the December 1 issue of JAMA . Adults with CP represent an increasing population whose health status and health care needs are poorly understood. Mortality records reveal that death due to ischemic heart disease and cancer is higher among adults with CP however, there have been no n ...
EurekAlert - Tue. Dec 1
New strategy discovered for treating arthritis
Arthritis patients could one day benefit from a novel form of medicine, according to researchers at Queen Mary University of London QMUL . Their early study indicates that arthritic cartilage, previously thought to be impenetrable to therapies, could be treated by a patient s own microvesicles that are able to travel into cartilage cells and deliver therapeutic agents. Microvesicles are very small subcellular structures 0.05 to 1 micrometer in diameter tha ...
EurekAlert - Fri. Nov 27
Gene identified that produces benefits of steroids, without the detrimental si...
Scientists have revealed that glucocorticoids, a class of steroid hormones that are commonly prescribed as drugs, enhance muscle endurance and alleviate muscular dystrophy through activation of the gene KLF15. Critically, this pathway is not involved in muscle wasting or the other major detrimental effects of prolonged steroid use. The discovery, published in The Proceedings of the National Academy of Sciences , could lead to the development of new medicat ...
EurekAlert - Mon. Nov 23