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UK study supports cardiovascular safety of calcium and vitamin D supplementation
UK researchers have presented a new study that supports the cardiovascular safety of calcium and vitamin D supplementation. The study was based on analysis of the UK Biobank, a very large study comprising 502,664 men and women aged 40-69 years. Of the total UK Biobank participants, 34,890 individuals 6.94 reported taking calcium supplements, 20,004 taking vitamin D supplements, and 10,406 taking both 2.1 . The researchers found no associations between the ...
EurekAlert - Sat. Apr 16
Farmers are not just the backbone of a nation, they may have stronger hips too
A team of UK and Swedish researchers has released the findings of a new study which assessed the hip fracture risk of farmers in Sweden. Sweden is one of the few countries which tracks hip fractures through a national registry. It is therefore possible to assess how hip fracture risk across the country varies according to occupation, economic status, level of education, latitude, and urban versus rural residence. Although hip fracture risk is known to be c ...
EurekAlert - Sat. Apr 16
Drug candidate stops extra bone growth in animal model of rare, genetic disease
PHILADELPHIA - New preclinical research provides support to a drug that has been repurposed to possibly treat a rare and extremely disabling genetic bone disease, particularly in children. In that disease, fibrodysplasia ossificans progressiva FOP , a mutation triggers bone growth in muscles, alters skeletal bone formation, and limits motion, breathing, and swallowing, among a host of progressive symptoms. The research appeared online in the Journal of Bon ...
EurekAlert - Wed. Apr 13
Would changing gait pattern decrease your likelihood of running injuries?
ROSEMONT, Ill. April 6, 2016 --Are runners less injury-prone trekking barefoot than in pricey running shoes Maybe, according to a new literature review in the March issue of the Journal of the American Academy of Orthopaedic Surgeons JAAOS . Advances in running shoe technology in the last 40 years have not reduced injuries, but racing barefoot in shoes with minimal cushioning could help runners change their strides and landing patterns to prevent repetitiv ...
EurekAlert - Thu. Apr 7
Young arthritis patients have unique concerns about treatment
They describe a wide range of consequences--physical, emotional, social, and vocational--arising from their treatment. The findings indicate that young arthritis patients need active encouragement to discuss their treatment concerns and difficulties, so that a balance can be achieved between disease control and treatment burden. Young people can have severe arthritis, warranting aggressive treatment, but may find such regimens a struggle to sustain. Encour ...
EurekAlert - Thu. Apr 7
For young people with schizophrenia, physical and mental exercises offer hope
In as little as a few months, antipsychotic medications can tame the delusions and hallucinations that characterize schizophrenia. But the medications do little to reverse the less familiar brain-based problems that accompany the illness. Affecting memory, the speed at which the brain processes information, attention, problem-solving skills and emotional intelligence, these subtle but profound deficits can prove more crippling than schizophrenia s more dra ...
EurekAlert - Wed. Apr 6
Insights into new targets and promising treatments for musculoskeletal disease
Great progress has been made in the understanding of the genes and molecular pathways that contribute to the pathogenesis of bone and muscle diseases. As a result of these advances, several new molecular targets have been identified for drug design - knowledge which is being harnessed for the development of new treatment options for sarcopenia and metabolic bone diseases such as osteoporosis, hypophosphataemic rickets, and hypophosphatasia. A special issue ...
EurekAlert - Wed. Apr 6
Most patients likely to see reductions in pain and disability after bariatric ...
PITTSBURGH, April 5, 2016 - In the three years following bariatric surgery, the majority of patients experienced an improvement in pain and walking ability, as well as a lessening of the degree to which back or leg pain interfered with work, according a University of Pittsburgh Graduate School of Public Health-led analysis of a multi-site clinical study published today in the Journal of the American Medical Association . The study also revealed patient cha ...
EurekAlert - Tue. Apr 5
Risk of breaking a bone depends on where you live
Ethnicity, socioeconomic status and place of residence in the UK all influence the risk of breaking a bone, a new Southampton study has shown. Researchers at the Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, undertook an analysis of the UK Clinical Practice Research Datalink database and calculated the risk of an individual experiencing a fracture. They also examined whether this risk varied according to age, sex, ethnic ...
EurekAlert - Tue. Apr 5
Aromatase inhibitors plus growth hormone may help short adolescent boys grow t...
Boston, MA-- Aromatase inhibitors, when used for up to three years in combination with growth hormone, may effectively and safely help very short adolescent boys grow taller, new research suggests. The study results will be presented Sunday, April 3, at ENDO 2016, the annual meeting of the Endocrine Society in Boston. Treating the growth-retarded child in puberty presents significant challenges not easily overcome by the use of growth hormone GH alone, as ...
EurekAlert - Mon. Apr 4
Bone density lower with use of ADHD stimulant medicine
Boston, MA-- Children and teenagers who take stimulant drugs to treat attention-deficit hyperactivity disorder ADHD may have lower bone density than their peers who do not take these medications, a new study finds. The study results will be presented Friday at the Endocrine Society s 98th annual meeting in Boston. Stimulants, such as methylphenidate Ritalin and other brands and amphetamine, are frequently a treatment of ADHD, a condition that affects more ...
EurekAlert - Mon. Apr 4
SSRI antidepressants promote bone loss during lactation
Boston, MA-- Antidepressant use with selective serotonin reuptake inhibitors SSRIs during pregnancy and breast-feeding causes decreased bone density in mothers that may put them at higher risk of broken bones later in life, a new study suggests. Researchers will present the results of their animal study Friday at the Endocrine Society s 98th annual meeting in Boston. SSRIs are the most widely prescribed class of antidepressants, particularly during pregnan ...
EurekAlert - Mon. Apr 4