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Adults with cerebral palsy more likely to have chronic health conditions
Adults with cerebral palsy CP have higher odds for chronic health conditions such as asthma, hypertension and arthritis compared with adults without CP, according to a study in the December 1 issue of JAMA . Adults with CP represent an increasing population whose health status and health care needs are poorly understood. Mortality records reveal that death due to ischemic heart disease and cancer is higher among adults with CP however, there have been no n ...
EurekAlert - Tue. Dec 1
New strategy discovered for treating arthritis
Arthritis patients could one day benefit from a novel form of medicine, according to researchers at Queen Mary University of London QMUL . Their early study indicates that arthritic cartilage, previously thought to be impenetrable to therapies, could be treated by a patient s own microvesicles that are able to travel into cartilage cells and deliver therapeutic agents. Microvesicles are very small subcellular structures 0.05 to 1 micrometer in diameter tha ...
EurekAlert - Fri. Nov 27
Gene identified that produces benefits of steroids, without the detrimental si...
Scientists have revealed that glucocorticoids, a class of steroid hormones that are commonly prescribed as drugs, enhance muscle endurance and alleviate muscular dystrophy through activation of the gene KLF15. Critically, this pathway is not involved in muscle wasting or the other major detrimental effects of prolonged steroid use. The discovery, published in The Proceedings of the National Academy of Sciences , could lead to the development of new medicat ...
EurekAlert - Mon. Nov 23
NYU Langone enhances patient experience by reducing referrals to facilities af...
Referring a patient to an acute care facility following major cardiac, joint and spine surgery rather than the patient s own home may not always be necessary--according to findings of a new self-examining study from NYU Langone Medical Center. According to researchers, an approach to post-surgery care that the institution implemented two years ago--which included sharply reducing post-hospital referrals to acute care facilities--showed no corresponding inc ...
EurekAlert - Mon. Nov 23
Study quantifies risk of cardiac arrest in children during spine surgeries
Although the vast majority of pediatric spine surgeries are safe, a handful of neuromuscular conditions seem to fuel the risk of cardiac arrest during such operations, according to research led by investigators at the Johns Hopkins Children s Center. A report on the findings, published in the November issue of the journal Spine , is believed to be the first to quantify the risk -- which is quite small -- of this potentially lethal complication among childr ...
EurekAlert - Thu. Nov 19
Brain disorder may increase miscarriage and preeclampsia risk in pregnancy
MINNEAPOLIS - Neuromyelitis optica spectrum disorder, a disease often confused for multiple sclerosis, may increase a woman s risk for miscarriage and preeclampsia during pregnancy, according to a study published in the November 18, 2015, online issue of Neurology reg , the medical journal of the American Academy of Neurology. The disorder causes inflammation in the central nervous system, affecting mainly the spinal cord and the nerves to the eyes, althou ...
EurekAlert - Thu. Nov 19
Obesity spells problems for trauma patients
ROSEMONT, Ill.--A new study appearing in the November 18 issue of the Journal of Bone Joint Surgery JBJS found a link between obesity and a higher risk for surgery in orthopaedic trauma patients. In addition, researchers found that patients with obesity had longer hospital stays and greater treatment costs. They were also more likely to be discharged to a care facility, rather than to home. Obesity affects more than 38 percent of the American population. I ...
EurekAlert - Thu. Nov 19
Target gene identified for therapies to combat muscular dystrophy
Researchers at the University of S 227 o Paulo s Bioscience Institute IB-USP in Brazil have shown that a gene called Jagged1, or JAG1 for short, could be a target for the development of new approaches to treat Duchenne muscular dystrophy DMD , a genetic disorder characterized by progressive muscle degeneration. The research was carried out at the Human Genome Stem Cell Research Center HUG-CELL , one of the Research, Innovation and Dissemination Centers RID ...
EurekAlert - Fri. Nov 13
'No evidence' that bone-growth agent for spinal fusion increases cancer risk
November 12, 2015 - A new study may alleviate concerns regarding increased cancer risk for patients undergoing spinal fusion surgery with recombinant human bone morphogenetic protein rhBMP . The study appears in November 15 issue of Spine , published by Wolters Kluwer . Our study provides further evidence of rhBMP s efficacy as a fusion agent with no evidence of a significantly increased risk of cancer, write Dr. Gregory M. Malham of Epworth Hospital, Melb ...
EurekAlert - Thu. Nov 12
Pitt study: Chronic arsenic exposure can impair ability of muscle to heal afte...
PITTSBURGH, Nov. 10, 2015 - Chronic exposure to arsenic can lead to stem cell dysfunction that impairs muscle healing and regeneration, according to an animal study conducted by researchers at the University of Pittsburgh s School of Medicine and Graduate School of Public Health. In a report published online in STEM CELLS , they noted that inhibiting a certain protein in an inflammatory pathway can reverse the harmful effects and that environmental exposur ...
EurekAlert - Wed. Nov 11
Wrist fractures could predict susceptibility to serious fractures in postmenop...
Wrist fractures are common among postmenopausal women who are younger than 65 and a new UCLA-led study suggests that they may also predict more serious fractures in other parts of their bodies later in life. The researchers on the study, published in the November issue of the Journal of Bone and Mineral Research , found that one in five women who had experienced a broken wrist went on to suffer a non-wrist fracture during the next 10 years. They also said ...
EurekAlert - Wed. Nov 11
Poverty influences effects of race and education on pain after knee replacemen...
Non-white race and lack of education are known risk factors for pain and poorer function after knee replacement surgery. What isn t clear is how a community s poverty level affects the outcomes of having a joint replaced. Findings from a new study conducted by researchers from Hospital for Special Surgery HSS suggest that lower socioeconomic status at the community level significantly increases the risk of pain and poor function following a knee replacemen ...
EurekAlert - Mon. Nov 9