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New skin-graft system a better fix for chronic wounds
According to the National Institutes of Health, more than six million cases of chronic wounds cost 20 billion each year in the United States. Diabetic ulcers, pressure sores, surgical site wounds and traumatic injuries to high-risk patients account for most wounds that won t heal. However, data from a University of Missouri School of Medicine study indicates that a recently developed skin-graft harvesting system aids in chronic wound recovery and reduces c ...
EurekAlert - Fri. Feb 3
Gene therapy for Pompe disease effective in mice, poised for human trials
DURHAM, N.C. -- After decades investigating a rare, life-threatening condition that cripples the muscles, Duke Health researchers have developed a gene therapy they hope could enhance or even replace the only FDA-approved treatment currently available to patients. The gene therapy, demonstrated in mice, is described in a new study published online in the journal Molecular Therapy - Methods Clinical Development . The therapy uses a modified virus to deliver ...
EurekAlert - Sat. Jan 28
Anti-inflammatory diet could reduce risk of bone loss in women
COLUMBUS, Ohio - Anti-inflammatory diets -- which tend to be high in vegetables, fruits, fish and whole grains -- could boost bone health and prevent fractures in some women, a new study suggests. Researchers examined data from the landmark Women s Health Initiative to compare levels of inflammatory elements in the diet to bone mineral density and fractures and found new associations between food and bone health. The study, led by Tonya Orchard, an assista ...
EurekAlert - Sat. Jan 28
Examining women's bones during menopause may help head off fractures
ANN ARBOR, Mich. - Bone fragility has long been a worrisome condition affecting women as they age. It s been considered a silent disease, says Karl Jepsen, Ph.D. , associate chair of research and professor of orthopaedic surgery at Michigan Medicine, noting, One of the biggest challenges when you re looking at age-related bone fragility is to identify people who will fracture. Jepsen is the lead author on a new study , published in the Journal of Bone and ...
EurekAlert - Sat. Jan 28
Can yoga help with chronic back pain?
Lower back pain affects millions of people in the United States, and for some, the pain becomes chronic, preventing them from performing daily tasks. Could yoga help to treat this condition A new review investigates.
Medical News Today - Sat. Jan 28
New genomic tool for salamander biology could spur deeper understanding of tis...
A research team led by scientists at Brigham and Women s Hospital has assembled a catalogue of every active gene in a variety of tissues in the axolotl, a type of salamander known for its striking ability to fully regenerate limbs following amputation. The catalogue, known as a transcriptome, provides a important resource for the community of researchers who study axolotls -- a model organism that promises to shed light not only on the molecular mechanisms ...
EurekAlert - Tue. Jan 17
Experts seek to educate orthopaedic researchers on the ethical use of animals ...
Recent initiatives by the Orthopaedic Research Society seek to improve animal research and ensure that it is performed to the highest ethical and scientific standards. Part of the initiatives seek to provide new tools to educate researchers about alternatives to using animals and to train investigators on new techniques to improve animal study design and technical competence. A Journal of Orthopaedic Research article summarises the recent and ongoing initi ...
EurekAlert - Tue. Jan 17
Axial spondyloarthritis: Patients see sustained benefit with certolizumab pegol
Researchers are reporting that early rapid improvements in the signs and symptoms of axial spondyloarthritis in patients treated with certolizumab pegol are maintained at 4 years.
Medical News Today - Tue. Jan 17
Nonsurgical and surgical treatments provide successful outcomes for an Achille...
ROSEMONT, Ill. Jan. 9, 2017 --A new literature review published in the Journal of the American Academy of Orthopaedic Surgeons JAAOS found successful outcomes for an Achilles tendon tear with either minimally invasive surgery or nonsurgical bracing with a removable boot, especially in recreational athletes. The use of platelet rich plasma PRP , the injection of plasma-enriched platelets at the injury site, was not deemed an effective treatment. A tear rupt ...
EurekAlert - Wed. Jan 11
The weather's not to blame for your aches and pains
New research from The George Institute for Global Health has revealed the weather plays no part in the symptoms associated with either back pain or osteoarthritis. It s long been thought episodes of both back pain and arthritis can be triggered by changes in the weather, including temperature, humidity, air pressure, wind direction and precipitation. Professor Chris Maher, of The George Institute for Global Health, said The belief that pain and inclement w ...
EurekAlert - Wed. Jan 11
Yoga may have health benefits for people with chronic non-specific lower back ...
A new systematic review, published in the Cochrane Library today, suggests that yoga may lead to a reduction in pain and functional ability in people with chronic non-specific lower back pain over the short term, compared with no exercise. However, researchers advise that more studies are needed to provide information on long-term effects. Lower back pain is a common health problem, and is usually treated with self-care and over-the-counter medication. For ...
EurekAlert - Wed. Jan 11
Medicare bundled-payments model cut joint replacement costs by more than 20 pe...
PHILADELPHIA - Bundled payment models can push Medicare and health system costs down considerably without sacrificing quality of care, according to new research from the Perelman School of Medicine at the University of Pennsylvania. The study, the first to combine hospital cost and Medicare claims data to identify drivers of joint replacement cost savings - evaluated costs and care quality at for hip and knee replacements performed from 2008-2015 at the fi ...
EurekAlert - Sat. Jan 7