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Exploring future preventive strategies for patients at imminent risk of hip fr...
Hip fractures are of great concern as they are the most severe type of fracture in osteoporotic patients, associated with premature death, and commonly leading to long-term physical disability, impaired capacity to perform daily activities and live independently, and reduced quality of life. In the Western world, the lifetime risk for hip fracture in women over the age of 50 years is 18-23 and by 2050, the worldwide annual number of hip fractures is expect ...
EurekAlert - Mon. Dec 19
Stem cell 'living bandage' for knee injuries trialed in humans
A living bandage made from stem cells, which could revolutionise the treatment and prognosis of a common sporting knee injury, has been trialled in humans for the first time by scientists at the Universities of Liverpool and Bristol. Meniscal tears are suffered by over one million people a year in the US and Europe alone and are particularly common in contact sports like football and rugby. 90 or more of tears occur in the white zone of meniscus which lack ...
EurekAlert - Fri. Dec 16
Researchers add to evidence that common bacterial cause of gum disease may dri...
Investigators at Johns Hopkins report they have new evidence that a bacterium known to cause chronic inflammatory gum infections also triggers the inflammatory autoimmune response characteristic of chronic, joint-destroying rheumatoid arthritis RA . The new findings have important implications for prevention and treatment of RA, say the researchers. In a report on the work, published in the Dec. 14 edition of the journal Science Translational Medicine , th ...
EurekAlert - Wed. Dec 14
Creative approach to probing genome IDs genes that likely influence bone stren...
In an important step in the battle against osteoporosis, a serious brittle bone disease that affects millions, researchers have identified more than a dozen genes amid the vast human genome likely responsible for bone density and strength. The crafty approach the researchers used to find these genes - essentially identifying needles in a haystack - could speed the development of new and better treatments for osteoporosis and many other diseases. Narrowing ...
EurekAlert - Wed. Dec 14
Back pain may raise risk of mental health problems
A study, involving almost 200,000 participants, finds that individuals who have back pain are more likely to also experience a range of mental health issues. Knowing about these links could form a more successful treatment plan for both sets of conditions.
Medical News Today - Wed. Dec 14
Broken shoulder leads to carpal tunnel syndrome surgery study
Patients who undergo surgery for carpal tunnel syndrome can regain their typing ability within two or three weeks after the operation. That is the conclusion of a serendipitous research project that came about because a psychologist who studies the automatic response patterns involved in typing broke his shoulder. In 2009, Gordon Logan, Centennial Professor of Psychology at Vanderbilt University, put a stool on top of a chair to change a light bulb. The ar ...
EurekAlert - Tue. Dec 13
AAOS Board approves treatment criteria for carpal tunnel syndrome and knee ost...
Rosemont, Ill. --The American Academy of Orthopaedic Surgeons AAOS Board of Directors has approved new Appropriate Use Criteria AUC for the management of carpal tunnel syndrome CTS and the surgical management of osteoarthritis of the knee. The AUCs provide specific diagnostic criteria, complementing and building upon the clinical practice guidelines CPGs Management of Carpal Tunnel Syndrome and Surgical Management of Osteoarthritis of the Knee. The CPGs an ...
EurekAlert - Mon. Dec 12
Key regulator of bone development identified
Loss of a key protein leads to defects in skeletal development including reduced bone density and a shortening of the fingers and toes -- a condition known as brachydactyly. The discovery was made by researchers at Penn State University who knocked out the Speckle-type POZ Protein Spop in the mouse and characterized the impact on bone development. The research, which appears online in the journal Proceedings of the National Academy of Sciences on December ...
EurekAlert - Fri. Dec 9
Study: Running actually lowers inflammation in knee joints
We all know that running causes a bit of inflammation and soreness, and that s just the price you pay for cardiovascular health. You know no pain, no gain. Well, maybe not. New research from BYU exercise science professors finds that pro-inflammatory molecules actually go down in the knee joint after running. In other words, it appears running can reduce joint inflammation. It flies in the face of intuition, said study coauthor Matt Seeley, associate profe ...
EurekAlert - Fri. Dec 9
New gene therapy for pseudarthrosis trialed at Kazan University
A team headed by Professor Albert Rizvanov, director of the Gene and Cell Technologies Open Lab, created a gene therapy drug that encodes growth factors for the stimulation of blood vessel and bone formation. The combination was highly effective in a patient admitted to the Republican Clinical Hospital in Kazan, Russia. The treatment was approved by the ethical committee, supported by the Ministry of Healthcare of Tatarstan and published in BioNanoScience ...
EurekAlert - Fri. Dec 2
XROMM, an influential 3-D, X-ray technology for biomechanics, gains new capabi...
PROVIDENCE, R.I. [Brown University] -- It s right there in the word discovery -- the idea of removing whatever cover may obscure a particular phenomenon from observation. And that s exactly what Brown University s X-ray Reconstruction of Moving Morphology technology does to reveal the inner workings of people and animals. With two recent papers describing powerful new software and a way to track muscle contractions, XROMM can do even more than before. And ...
EurekAlert - Thu. Dec 1
NEOMED researchers identify link between brain and bone in Alzheimer's disease
ROOTSTOWN, OH--Researchers at NEOMED have just identified a major connection between areas of the brainstem - the ancient area that controls mood, sleep and metabolism - and detrimental changes to bone in a preclinical model of Alzheimer s disease AD . The study, titled Early Evidence of Low Bone Density and Decreased Serotonergic Synthesis in the Dorsal Raphe of a Tauopathy Model of Alzheimer s Disease, is led by Christine Dengler-Crish, Ph.D., assistant ...
EurekAlert - Thu. Dec 1